Spravato

Spravato® (Esketamine) for Treatment-Resistant Depression

Many people come in worried about attention or executive function—and discover that the bigger issue is depression: low energy, low drive, poor sleep, and a heavy emotional fog that makes everything harder to do.

If depression has not improved enough with standard treatment, we may discuss Spravato® (esketamine)—an FDA-approved option for treatment-resistant depression—delivered in a certified clinical setting with required monitoring.

When you can’t focus because you’re carrying too much

Dopamine Trust Serotonin

What Spravato® is

Spravato® (esketamine) is a prescription nasal spray used for adults with:

Patients often explore TMS for:

It is provided in a certified medical setting under a required safety program (REMS), with on-site monitoring.

Who may be a good candidate

Spravato® may be considered if you:

Eligibility is determined during a clinical evaluation.

What to expect

Evaluation

We’ll review your symptoms, treatment history, medical history, and current medications to determine safety and fit.

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In-clinic treatment visits

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Ongoing plan

Spravato® is typically part of a broader plan that may include medication management and therapy coordination, based on your needs.

Safety & important considerations

Spravato® can cause side effects that require monitoring, including:

We’ll review risks, precautions, and what to do before/after visits so you feel prepared and supported.

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Insurance & cost

Coverage varies by plan, but Spravato® is often covered when criteria for TRD are met. We can help you understand:

Frequently Asked Questions

No. It must be administered in a certified clinical setting with monitoring.

Some patients notice changes earlier than with traditional treatments, but response varies. We track progress carefully over time.

We’ll still help you map a next-step plan—whether that’s medication optimization, therapy coordination, TMS, or other evidence-based options.

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Ready to explore next steps?

If you’re wondering whether Spravato® is right for you, start with a conversation. We’ll keep it clear, honest, and pressure-free.

Eligibility is determined during a clinical evaluation. Individual results vary and no outcome can be guaranteed. Spravato® is provided under required safety monitoring in accordance with applicable regulations.