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Both Spravato (esketamine) and IV ketamine work fast for treatment-resistant depression. Here's how they differ in FDA approval, safety oversight, insurance coverage, and clinical evidence — and why our practice offers Spravato. By Nefretiri Abat,
Read MoreFor most patients with TRD, SPRAVATO and TMS can be combined or sequenced. Here's what the evidence says — and how we sequence at Exxceed Wellness.
Read MoreWhy Spravato (esketamine) acts in 24 hours when SSRIs take six to eight weeks — and why the dissociation patients fear is not the antidepressant. A patient-first walkthrough of the NMDA → AMPA → BDNF
Read MoreA patient-facing clinical guide to the FDA/EMA two-failed-trials standard for diagnosing treatment-resistant depression — what counts as an adequate trial, why pseudoresistance must be ruled out first, and what comes next. By Nefretiri Abat, PMHNP-BC,
Read MoreA 2026 clinical guide to treatment-resistant depression: definitions, pseudoresistance workup, evidence-based treatments including SPRAVATO monotherapy, SAINT, and a 10-step management algorithm. By Nefretiri Abat, PMHNP-BC, JD.
Read MoreOCD isn’t a matter of willpower or personality — it’s a pattern in specific brain circuits, and understanding that pattern helps explain why the evidence-based treatments work. The loop behind the symptoms Researchers consistently implicate
Read MoreIf you’re dealing with severe clinical depression, the kind that does not lift with a few lifestyle changes or a few months of talk therapy, you’ve probably already lived through the long list: medication switches,
Read MoreIf you’ve searched “TMS for OCD,” here’s the honest, useful version — what the treatment actually is, and how to get evidence-based OCD care whether or not TMS is the right path for you. “TMS
Read MoreLiving with chronic neuropathic pain can feel relentless. That burning, shooting, electric, or pins-and-needles sensation from damaged nerves doesn’t just hurt—it disrupts sleep, work, and even simple daily tasks. Common causes include diabetic neuropathy, pain
Read MoreFor many people with long COVID, the acute infection is long over, but the nervous system never fully recalibrated. Persistent symptoms such as cognitive fog, mental fatigue, mood disruption, and reduced executive function suggest an
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