How Much Does Spravato Cost in California?

How much does Spravato cost in California?

Without insurance, Spravato costs roughly $600 to $900 for the medication per session (56 mg or 84 mg dose), plus a facility and monitoring fee, for a total that commonly reaches $1,000 to $1,500 per supervised session. With insurance, most patients pay $10 to $250 per session after prior authorization. An eligible commercially insured patient may pay as little as $10 per treatment through the manufacturer savings program.

Spravato is FDA-approved, which generally results in broader insurance coverage than off-label treatments.

What drives the cost

• The medication. Esketamine is billed per dose, either 56 mg or 84 mg. The dose is set by the treatment phase and clinical response.
• Supervised administration. Spravato is self-administered in a certified healthcare setting under a federal safety program (REMS), with about two hours of monitoring after each dose.
• Treatment schedule. Induction is twice weekly for the first four weeks, followed by a maintenance phase at a reduced frequency.

Spravato cost with insurance

Spravato is FDA-approved for treatment-resistant depression and for major depressive disorder with acute suicidal ideation or behavior. Most commercial plans, Medicare, and Medi-Cal cover it with prior authorization.

• Commercial insurance. Plans including UnitedHealthcare, Aetna, Cigna, and Anthem cover Spravato with prior authorization. Most insured patients pay their standard specialist cost-sharing.
• Medicare. Medicare Part B covers Spravato administered in a certified facility, generally paying 80 percent of the approved amount after the deductible. A supplement plan may cover the remaining share.
• Medi-Cal. Medi-Cal covers Spravato for treatment-resistant depression with prior authorization.

Prior authorization generally requires documentation of treatment-resistant depression, defined as an inadequate response to at least two antidepressant medications.

The Spravato savings program

The manufacturer offers a savings program for eligible patients with commercial insurance. It can reduce the out-of-pocket medication cost to as little as $10 per treatment, up to program limits. Patients with government insurance, including Medicare and Medi-Cal, are not eligible for the manufacturer program; their cost-sharing is set by their plan.

Spravato cost without insurance

• Medication: about $600 to $900 per dose.
• Per supervised session, including monitoring: commonly $1,000 to $1,500.
• The first month of induction is the most expensive phase. Maintenance costs less because sessions are less frequent.

Spravato compared with IV ketamine

Spravato (esketamine) is FDA-approved and is frequently covered by insurance. Intravenous ketamine for depression is used off-label and is often not covered, which shifts its cost to self-pay. For a patient with insurance and treatment-resistant depression, Spravato is often the lower out-of-pocket option once coverage is applied.

How we handle Spravato cost

Exxceed Wellness provides Spravato in a certified setting in Hayward, CA. We verify your benefits, complete the prior authorization, and review savings-program eligibility before treatment begins. See our Spravato program, our fees and insurance page, or contact us.

Frequently asked questions

Does insurance cover Spravato?

Most commercial plans, Medicare, and Medi-Cal cover Spravato for treatment-resistant depression with prior authorization, because it is FDA-approved for that use.

How much is Spravato with insurance?

Most insured patients pay $10 to $250 per session. Eligible commercially insured patients may pay as little as $10 per treatment through the manufacturer savings program.

How much is Spravato without insurance?

About $600 to $900 for the medication per dose, or roughly $1,000 to $1,500 per supervised session including monitoring.

Does Medicare cover Spravato?

Medicare Part B covers Spravato administered in a certified facility, generally at 80 percent of the approved amount after the deductible.

References

1. SPRAVATO (esketamine) insurance coverage information, manufacturer: spravato.com.
2. Medicare coverage of esketamine (Spravato): Medicare.org.
3. Cost-per-remitter for esketamine nasal spray versus quetiapine for treatment-resistant depression: PMC.

Educational information only, not medical or financial advice. Spravato costs and coverage vary by dose, plan, provider, and treatment phase, and can change. Spravato is FDA-approved for treatment-resistant depression and for major depressive disorder with acute suicidal ideation or behavior; it is administered only in a certified setting with monitoring. Confirm your eligibility, coverage, and out-of-pocket cost with a qualified clinician and your health plan.

Care at Exxceed Wellness — Hayward, CA & California telehealth. We provide Spravato (esketamine) nasal spray for treatment-resistant depression — REMS-certified, in office; it is the only ketamine-route treatment we offer. Learn more ›, schedule a consultation, or call (415) 636-9700.