
What If Neither SPRAVATO Nor TMS Works for Me?
If you have completed both SPRAVATO and TMS without the response you needed, you are not at the

If you have completed both SPRAVATO and TMS without the response you needed, you are not at the

You’ve tried two antidepressants. Now your psychiatrist is talking about Spravato — or TMS. A specialist breaks down

Both Spravato (esketamine) and IV ketamine work fast for treatment-resistant depression. Here’s how they differ in FDA approval,

For most patients with TRD, SPRAVATO and TMS can be combined or sequenced. Here’s what the evidence says

Why Spravato (esketamine) acts in 24 hours when SSRIs take six to eight weeks — and why the

A patient-facing clinical guide to the FDA/EMA two-failed-trials standard for diagnosing treatment-resistant depression — what counts as an

A 2026 clinical guide to treatment-resistant depression: definitions, pseudoresistance workup, evidence-based treatments including SPRAVATO monotherapy, SAINT, and a

In 2019, a multicenter, randomized, double-blind clinical trial published in The American Journal of Psychiatry reported something significant:

If you’re dealing with severe clinical depression, the kind that does not lift with a few lifestyle changes

In 2019, a multicenter randomized controlled trial published in The American Journal of Psychiatry found that targeted transcranial

Living with chronic neuropathic pain can feel relentless. That burning, shooting, electric, or pins-and-needles sensation from damaged nerves

If depression, anxiety, PTSD, or persistent burnout has been weighing you down—making even the basics feel overwhelming—we see

We may be entering an era where “ADHD treatment” does not automatically mean “start (or change) a medication.”

For many people with long COVID, the acute infection is long over, but the nervous system never fully

Multiple randomized controlled trials and meta-analyses now show that repetitive Transcranial Magnetic Stimulation (rTMS) can significantly reduce symptoms

Transcranial Magnetic Stimulation (TMS) occupies a specific regulatory and financial position in California healthcare: it is an FDA-cleared